- Diabetes Research
- Glucose Meters
- Adult Onset Diabetes
- Diabetes and Exercise
- Diabetes and Insurance
- Diabetes and Sex
- Diabetes Care
- Diabetes Control
- Diabetes Cure
- Diabetes Prevention
- Diabetes Technology
- Insulin Resistance
- Type 1 Diabetes
- Type 2 Diabetes
- Type 3 Diabetes
- Battle Diabetes
Kids who exercise can undo damage of maternal obesity
It's possible the detrimental health effects maternal obesity has on children can be avoided – or at least minimized – if kids are active during adolescence, a new study reports.
Researchers from Johns Hopkins used an animal model to examine rats whose mothers were fed a high-fat diet during pregnancy and nursing. Some of the offspring were given free access to running wheels in their cages, while others had to remain sedentary.
Despite the fact that both the active and sedentary rats weighed the same, the rats who exercised had fewer fat deposits – and also showed heightened sensitivity to hormones that regulate appetite, even after they stopped running on their exercise wheels.
To examine how exercise influenced appetite, the researchers injected the rats' brains with the appetite-suppressing hormone leptin when they were 14 weeks old. Leptin is secreted naturally by fat cells, helping the body to regulate hunger and maintain a healthy weight. In obese people, however, leptin levels are usually higher in the bloodstream, causing individuals to develop an insensitivity to the hormone. Eventually their brains stop responding to it, said study leader Kellie L. K. Tamashiro.
After being injected with leptin, the rats who had exercised tended to eat less, while the sedentary rats didn't show any changes in appetite.
"There was something about the exercise that improved their leptin sensitivity, even the equivalent in humans of years later," Tamashiro said.
The study suggests that exercise might enable human brains to respond better to lepton – and therefore help people to eat less, the researchers said.
Previous studies by Tamashiro and her team have shown that rats born to mothers fed high-fat diets can avoid obesity and related health disorders if the offpsring get normal levels of dietary fat right after birth.
"Our research suggests that efforts to increase activity in kids could have positive long-term effects, regardless of whether they continue to exercise into adulthood," Tamashiro concluded.
Source: Johns Hopkins Medicine
The information provided on battlediabetes.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational and educational purposes. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of battlediabetes.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. Please see our Legal Statement for further information.
Subscribe today and receive a dietician-written meal plan!