Full results from a year long trial involving over 3,700 overweight and obese patients taking the drug liraglutide (Saxenda) show that patients receiving the drug lost more weight than those given placebo.
[For the sake of clarification: Liraglutide is a glucagon-like peptide-1 receptor. In the treatment of type 2 diabetes it is sold under the brand name Victoza. For weight loss, liraglutide has been reformulated and sold under the brand name Saxenda.]
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In this study:
This study was led by Xavier Pi-Sunyer, MD, at Columbia University in New York City, and the team reported their findings in the 2 July 2015 issue of the New England Journal of Medicine.
"The treatment effect was similar in patients with prediabetes and those without prediabetes and was similar across body mass index categories," wrote Pi-Sunyer and colleagues.
In addition, the researchers found that there was a greater reduction in glycated hemoglobin, fasting glucose, and fasting insulin levels in the liraglutide group than in the placebo group.
Sources:
MedPage Today
NEJM
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