Diabetes Medication Could Make You Eat Less
Certain medications used to treat diabetes can also reduce food intake, according to a new study.
Researchers from Sahlgrenska Academy found that drugs like Byetta and Victoza mimic the gut-brain hormone GLP-1, which then affects the brain's reward system when it comes to eating.
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A follow-up study from the same research team also found that these drugs might also reduce alcohol intake.
"The results are increasing our understanding of how these medications can affect the brain," said Rozita Anderberg, Researcher at Sahlgrenska Academy.
The role of GLP-1
GLP-1 is a naturally occurring hormone in both the intestines and the brain. After eating, levels of GLP-1 increase, which leads to a rise in insulin and suppressed appetite.
Medications that act on the GLP-1 hormone for diabetes control have been used in recent trials for combating obesity.
Researchers found that these types of drugs can also stimulate the production of interleukin 6 and interleukin 1, hormones linked to immune system function in parts of the brain that regulate appetite.
"Our data can make an important contribution to the understanding of these mechanisms," says Rozita Anderberg, Researcher at Sahlgrenska Academy.
Source: University of Gothenburg
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