Diabetes Medications Could Reduce Risk for Dementia

A drug commonly used to treat diabetes could help to reduce risk for dementia, according to a new study from German researchers.

Patients with type 2 diabetes have a greater risk for developing dementia than non-diabetic individuals, the researchers explained, and long-term treatment with pioglitazone could help to reduce risk of cognitive decline.

"Treatment with pioglitazone showed a remarkable side benefit," said study investigator Gabriele Doblhammer. "It was able to significantly decrease the risk of dementia. The longer the treatment, the lower the risk."

Pioglitazone is taken in tablet-form and is used for both short- and long-term diabetes treatment.

Insulin and nerve protection

Diabetic patients taking pioglitazone had about a 47 percent lower risk of dementia than non-diabetics, and the drug seemed to be most effective when taken for at least 24 months.

Pioglitazone appears to protect nerve cells against inflammation and damage-causing proteins in the brain, while it also helps to improve the body's own insulin response.

While not as effective as pioglitazone, metformin, another popular diabetes drug, was also linked to a reduced dementia risk.

"Our study suggests that pioglitazone has a preventive effect," said study co-author Michael Heneka. "This happens when the drug is taken before symptoms of dementia manifest. Thus, it protects in particular against Alzheimer's, the most common form of dementia."

The researchers aren't sure whether the protective properties of pioglitazone would also help non-diabetic patients prevent cognitive impairment as they age.

The study is published in Annals of Neurology.

Source: Science Daily

Image courtesy of amenic181/FreeDigitalPhotos.net

Get a Free Diabetes Meal Plan

Get a free 7-Day Diabetes Meal Plan from Constance Brown-Riggs who is a Registered Dietitian-Certified Diabetes Educator and who is also a national spokesperson for the American Dietetic Association.

Just enter in your email below to download your free Diabetes Meal Plan.

By clicking Submit, you agree to send your info to BattleDiabetes.com who, in addition to 3rd party partners, may contact you with updates, products and information and we agree to use it according to our privacy policy and terms and conditions.

More Articles

More Articles

Scientists have discovered that a single gene forms a common link between type 2 diabetes and...

Natural supplements like cinnamon extract and apple cider vinegar could hold the key to lowering blood sugar levels, according to a recent...

Natural supplements like cinnamon extract and apple cider vinegar could hold the key to lowering blood sugar levels, according to a recent...

Could a person's risk for type 2 diabetes be written in their genes?

According to a study recently published in ...

Women who frequently shift around their sleeping hours could have worse metabolic health outcomes than their peers who stick with a...

The presence of the hormone leptin may hinder prenatal development, which could explain the origin of type 2 diabetes, according to...

An analysis of fossilized Native American feces shows that our ancestors ate up to sixteen times the fiber that we do today, but our...

Managing diabetes is hugely challenging for people of any age, but a new study suggests that young people may suffer all the more....

Disruptions to the gut’s ecosystem could be a future symptom facing young children who take antibiotics, which makes them more susceptible...

Breastfeeding a newborn holds many benefits for mommy and baby; it reduces the baby's risk for colds and viruses, it helps his bones (and yours)...

Fans of the Dexcom G5 Mobile have something to smile about.

At yesterday's hearing with the U.S. Food and Drug...

If you start your day with a cup of tea and end it with a glass of red wine, your blood sugar may thank you.

At least that...

As medical experts continue to debate whether or not "healthy obesity" can even exist, one new study suggests that risk for heart disease...

For years, type 1 diabetics have been anxiously waiting for that medical marvel that can stop the constant injections: the artificial...

“Low-fat” has been the battle cry of the health-conscious for over ‌‌‌‌‌‌‌‌‌‌‌...