Drug Could Spur Weight Loss in Patients With Type 2 Diabetes

Daily injections of diabetes drug liraglutide may help patients with type 2 diabetes lose weight, according to a new study published in JAMA.

The study, which included 846 overweight or obese patients with type 2 diabetes, had the participants taking either once-daily injections of liraglutide or a placebo for 56 weeks.

Results showed that participants taking a 3.0-mg dose of the drug lost about 14 pounds over the course of the study, while patients taking the placebo only lost 4.8 pounds, on average. Even participants taking lower doses of the drug lost more weight than the placebo group.

An adjunct to a healthy lifestyle

The authors said that liraglutide could be an adjunct to increased exercise and a lower-calorie diet for diabetes patients who are trying to lose weight.

Patients with type 2 diabetes are often advised to lose about 5 to 7 percent of their body weight, which can drastically help improve glycemic control and reduce risk for other complications of diabetes.

Liraglutide may help with weight loss by reducing appetite and slowing down the rate at which the stomach empties itself.

"To our knowledge, this is the first study specifically designed to investigate the efficacy of liraglutide for weight management in patients with type 2 diabetes and also the first study to investigate liraglutide at the higher 3.0-mg dose in a population with type 2 diabetes," the authors wrote.

Source: The JAMA Network Journals, Medical News Today
Image courtesy of phasinphoto/FreeDigitalPhotos.net

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