Regulatory Protein Lowers Blood Sugar Levels
Researchers at the Children's Hospital in Boston, led by Umut Ozcan, MD, have found a regulatory protein that lowers blood sugar levels when it is high due to either lack of insulin or a decreased sensitivity to insulin.
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Regulatory Protein - XBP-1s
XBP-1s regulates blood sugar, by causing the “degradation of FoxO1. FoxO1 increases glucose output from the liver and stimulates feeding behavior in the brain. Therefore, degrading FoxO1 reduces blood glucose levels and increases glucose tolerance (faster clearance of glucose from the blood).” It is also helpful when insulin sensitivity is a result of obesity.
Conclusion
By activating the XBP-1s it could be very beneficial to both type 1 and type 2 diabetics. The XBP-1s when used in a lab setting with mice significantly lowered their blood glucose levels. This is also possible for humans and could result in controlling a persons blood sugar levels with a minimal or in some cases no insulin.
Source: http://www.diabeteshealth.com/read/2011/02/23/7066/regulatory-protein-lo...
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