Type 2 Diabetes Increases Colorectal Cancer Risk

Patients with type 2 diabetes have an increased risk of developing colorectal cancer, according to new research.

A study conducted at Utrecht University in the Netherlands included 300,039 adults with diabetes who were taking at least one prescription medication for the condition.

Comparing data on these individuals with data on individuals without type 2 diabetes, researchers found that type 2 diabetes was linked to an increased risk of colorectal cancer in the more advanced stages of diabetes treatment.

"In summary, we observed a moderate, yet (1.3-fold) significantly increased, risk of colorectal cancer in patients treated for type 2 diabetes," the researchers wrote in Diabetes Care. "Among diabetic patients, an additional 1.2- to 1.3-fold increased risk was observed for patients who suffered from obesity for a total duration of four years or more."

The insulin factor

According to the researchers, the study suggests that long-term exposure to high levels of insulin can increase colorectal cancer risk.

The longer a patient with type 2 diabetes remains obese, moreover, the higher the risk is for this type of cancer.

"Future studies could determine whether the increased risk observed here is reversible through weight loss," the researchers wrote.

Source: Diabetes.co.uk

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