Viagra May Help Improve Insulin Sensitivity

People who are at risk for diabetes may benefit from the drug sildenafil, which is sold as Viagra, a new study reports.

Researchers from Vanderbilt University say sildenafil can improve insulin sensitivity by inhibiting an enzyme called phosphodiesterase 5 (PDE5), which enables increased blood flow, muscle relaxation and vasodilation - or the dilation of blood vessels. The drug can also help the uptake of glucose from the bloodsteam by muscle, which lowers levels of circulating glucose.

"Sildenafil and related drugs could offer a potential avenue for addressing the rising number of diabetes diagnoses," said Dr. Nancy J. Brown, chair of the Department of Medicine at Vanderbilt.

A long-term solution?

The study included overweight individuals with prediabetes who were randomly assigned to receive either sildenafil or a placebo for three months.

At the study's conclusion, patients taking sildenafil were "significantly" more sensitive to insulin, the researchers reported.

"Further studies will be needed to determine whether long-term treatment with drugs like sildenafil can prevent the onset of diabetes in high-risk patients," Brown said.

The study is published in The Journal of Clinical Endocrinology & Metabolism.

Source: Science Daily

More Articles

More Articles

Diabetics should avoid white bread and anything else made with white flour because it can raise their...

Diabetic shock occurs when blood sugar levels plummet, causing a disruption in the proper functioning of the body and brain. A significant drop in...

Diabetics are prone to boils because they have weakened immune systems. Boils are abscesses of infected skin that form near hair follicles. They...

One of the most important habits for diabetics to develop is a healthy exercise routine. If you’re...

Managing diabetes means not only monitoring your blood sugar but also following a healthful diet. Knowing...

Once widely known by the name "juvenile diabetes," type 1 diabetes is becoming more common. The disease occurs when the body starts attacking...

The American Heritage Dictionary defines homeostasis as a state of equilibrium, as in an organism or cell, maintained by self-regulating processes...

There are two types of diabetes, and both children and adults can develop either type....

The Mayo Clinic Diabetic Diet consists of ...

It is important for people with type 2 diabetes to follow a carefully recommended diet plan. The U.S....

According to the Mayo Clinic, excessive alcohol consumption can increase a person's risk of developing type 2...

With diabetes, your blood sugar levels...

It's important to follow a healthy diet if you have diabetes. Maintaining a frequent and nutritious eating schedule helps stabilize blood sugar...

Diabetic test strips are one of the biggest expenses in diabetes care. People who are on a fixed income need to watch every penny that they spend...

Many diabetics are told by their doctors to completely eliminate bread from their diet. While store-bought white bread is one of the worst foods a...